Feb 20, 2022
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Mesomorph Pre Workout : Old VS New 2022 UPDATE

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What Is Mesomorph | Original Mesomorph | Mesomorph in 2020 | Mesomorph V3 VS V4 | Mesomorph Reviews | Mesomorph Alternatives
The post Mesomorph Pre Workout : Old VS New 2022 UPDATE appeared first on Supplement Reviews Blog.


What Is Mesomorph | Original Mesomorph | Mesomorph in 2020 | Mesomorph V3 VS V4 | Mesomorph Reviews | Mesomorph Alternatives  | Side Effects And Warnings | Disclaimer

We all want to be the biggest and strongest we can be. When it comes to getting into shape and working out, there are a lot of factors that go into it. Diet, training, and even supplementation play a part in how you look and perform. So when it comes to improving our performance and getting the most out of every gym hit it’s no surprise that we look for products to get us in the zone. That’s where pre workouts like Mesomorph come into play. In this post, we’ll be covering Mesomorph pre workout today, formula revisions, reviews, and what compares!  

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What Is Mesomorph:

Mesomorph Pre Workout has held the crown for being one of the top pre workouts since it was first introduced to the fitness world around 2013. If you’ve been a fan of the OG Mesomorph and have continued to show it loyalty throughout the years, you know its had a bunch of revisions since then. Even through all the new looks and new formulas, the King of pre workouts has held it’s reign strong.

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The Original Mesomorph:

Even in the beginning, Mesomorph wasn’t a pre workout for beginners. Despite being a proprietary blend, the formula brought full, clinical dosages of it’s ingredients. Which supported a potent delivery of the energy, focus, and pumps complexes Mesomorph is known for. Below we have the original Mesomorph supplement facts.

Mesomorph Tutti Frutti Supplement Facts

Here you can see the classic 3 complexes in Mesomorph:

  • Synthenox-Carnosine/Nitric Oxide Complex
  • Mesoswell-Cell Volumizing ATP Matrix
  • Neuromorph-Neuro Energized Stimulant Matrix

All these complexes add together for a total of 12,870mg of active ingredients divided into 14 ingredients. Interestingly, the formula for Mesomorph doesn’t change significantly despite changing several times. In fact, the only complex that changes is the last one! Meaning both the Nitric Oxide Complex and Cell Volumizing Matrix have remained untouched since 2013!

Synthenox-Carnosine/Nitric Oxide Complex:

Now that we know this complex was able to stand the test of time, it’s time to go through the ingredients. In this blend of 6,500mg, there are 3 ingredients:

  • Beta Alanine
  • L-Citrulline DL-Malate
  • Arginine Alpha Ketoglutarate (AAKG)

This complex is going to focus on promoting endurance and blood flow.  (1,2,3)

Mesoswell-Cell Volumizing ATP Matrix:

In the next blend of 4,500mg, there are 6 ingredients:

  • Di-Creatine Malate
  • L-Taurine
  • Creatine Nitrate
  • Ascorbic Acid (Vitamin C)
  • Creatinol-O-Phosphate
  • Agmatine Sulfate

The majority of these ingredients support hydration for your muscle cells and reducing muscle fatigue. This helps creating a fuller look to your muscles while also boost ATP and recovery. Adding vitamin C can reduce cortisol levels allowing for longer lasting workouts and decreased soreness. (4,5,6,7,8,9,10,11)

Neuromorph-Neuro Energized Stimulant Matrix:

In this last blend, there was 1,870mg of active ingredients, which consisted of:

  • Glucoronolactone
  • Methylxanthine Anhydrous (Caffeine)
  • 3,7-dihydro-3,7-dimethyl-1H-purine-2,6-dione (Theobromine)
  • Naringin (fruit)
  • Geranaburn™ (DMAA)

This last blend is where you’ll find the stimulants and focus-oriented ingredients like Caffeine and DMAA.  (12,13,14,15,16)

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Mesomorph In 2020:

Before we get to the current version of Mesomorph, let’s go over changes from the OG to the version available in 2020, Mesomorph V3. This version of Mesomorph pre workout had 1860 mg of the Neuromorph matrix. In the older formula this matrix had 1870mg and contained 3,7-Dihydro-3,7-Dimethyl-1H-Purine-2, 6-Dione, and of course Geranaburn or DMAA.

In the updated V3 formula, this matrix featured:

  • Senegalia Berlandieri Extract
  • Phenylethylamine Alkaloids
  • Theobromine
  • Isopropylnorsynephrine HCl

Comparison Visual: Mesomorph Pre Workout Old DMAA VS New V3 Label


Starting from the beginning of the old label we have the ingredient 3,7-Dihydro-3,7-Dimethyl-1H-Purine-2, 6-Dione. This is actually just another name for Theobromine, so its technically not a change to the formula. Theobromine is a xanthine alkaloid that is used as a bronchodilator and as a vasodilator derived from Theobroma, the genus of the cacao tree.

It is the primary alkaloid found in cocoa and chocolate, and is one of the causes for chocolate’s mood-elevating effects. Theobromine is closely related to caffeine. However unlike caffeine, theobromine has an additional methyl group, making it’s effects last longer.

So what type of effects can you expect?

Because theobromine is similar to caffeine, you can expect the energy boost, as well as the mood boosting properties. Theobromine also has appetite suppressant properties which makes it a useful fat burning ingredient. (17)


Geranaburn™ (1,3-Dimethylamylamine HCL) or more commonly known as DMAA was the main stimulant in the original mesomorph pre workout. DMAA is structurally similar to ephedrine, with the quick energy spike associated with stimulants like caffeine. DMAA  helped boost dopamine and noradrenaline uptake, while slowing down the re-uptake for your workout. Which helps promote intense energy, while providing you tunnel like focus, and euphoria.†

Essentially the only ingredient changed from the original formula is the DMAA. 

The Stimulants

The first intense stimulant shown in the updated label is Senegalia Berlandieri Extract. It’s going to promote an increase energy, appetite suppression, while also providing a feeling of euphoria.(18) This ingredient is becoming very popular in fat burners because of these properties. Isopropylnorsynephrine HCl is the other intense stimulant in this matrix.†  It’s also known as Octopamine and is another alkaloid found alongside Synephrine in Citrus Aurantium. Aside from boosting energy, octopamine promotes fat burning by inhibiting the uptake of glucose in fat cells (adipocytes) by blocking the beta-3 adrenoceptor. (19)


Following Senegalia Berlandieri, we see Phenylethylamine (PEA) and its alkaloids, which are yielded from Senegalia. PEA is also a natural stimulant our bodies produce to serve several important functions. This includes supporting regulation of our mood. Like most stimulants PEA produces increased mood, focus, and energy. But what makes PEA special is it’s euphoric feeling. As seen with theobromine, PEA can be found in natural substances like chocolate. Both Phenylethylamine and theobromine help stimulate the production of endorphins, which is commonly known as your ‘feel-good’ hormone. (20,21)

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Mesomorph V3 VS V4 :


In November 2020,  Mesomorph pre workout had another formula revision, which is the current version (V4).

The V4 formula now contains:

  • 2-Aminoisoheptane HCl
  • Geranium Extract (stem & leaves)
  • Quebracho Blanco Extract

This also resulted in the removal of Senegalia Berlandieri Extract, all the Phenylethylamine Alkaloids, and Isopropylnorsynephrine HCl.

However, the rest of the formula is the same! This include the amounts of the proprietary blends and the other proprietary blend ingredients. 

Comparison Visual: Mesomorph Pre Workout V3 VS New V4

This first change is from Senegalia Berlandieri to 2-Aminoisoheptane or DMHA. This ingredient may help improve performance and increase weight loss as a stimulant. And is commonly compared to that of DMAA. (22) You can read more about DMHA HERE.

The next ingredient may bring you false hope, if you didn’t know, Geranium Oil is actually the source of DMAA (23). Unfortunately, seeing this in the formula doesn’t mean DMAA is in the newest version of Mesomorph. Just to repeat: There is no DMAA in Mesomorph as of December 2021. 

So what’s the point of this ingredient? While Geranium Extract is featured in this formula, it’s stripped of the DMAA Alkaloids. So what’s left is a potentially similar, but weaker version of this stimulant. However, we don’t have studies on the effectiveness of this extract like we do of other extract prepared in this manner (ephedra). 

The last change is the addition of Quebracho Blanco Extract which may act as vasodilator and aphrodisiac.(24)

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What Flavors Are Available?

Below we have listed the flavors available…in order of ranking popularity.

  1. Rocket Pop
  2. Tropical Punch
  3. Green Apple Candy
  4. Pink Lemonade
  5. Tutti Frutti
  6. Snow Cone
  7. Grape
  8. Watermelon
  9. Carnival Cotton Candy
  10. Pineapple

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What To Expect With Mesomorph V4?

With all these additions accounted for, Mesomorph is still going to be a strong pre workout. However, unlike in the previous formula, you most likely won’t get that surge of energy. Based on these new additions there is going to be a strong focus aspect to this pre workout, as well as the mood enhancement. 

The energy is still there and we would definitely recommend you assess your tolerance before taking a full scoop. This version has more of a sustainable energy blend, meaning when you feel it, it’ll last. So far based off of our teams experience Mesomorph pre workout is still the King of Pre workouts. But in 2022, customer reviews tend to be mixed. Some customers favor Mesomorph V3 with Senegalia over the V4 with DMHA. 

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Mesomorph Reviews :

And despite all the changes we see Mesomorph holding onto it’s reign and the customer reviews show that as well!

Review By Anthony

“Unfortunately when DMAA went away so did the ease of becoming easily focused to workout. But the few that abused that ingredient made the rest of us pay for it. Fortunately the new Mesomorph still packs a punch to help keep you energized till the end of your workout. As with any pre-work supplement you MUST cycle off to continue to see the benefits. Thank you for your customer service and above average shipping times!” Posted On 7/02/2021

 Review by Armando
“Definitely gets you up and running for an extense workout session – Even if you are tired and not wanting to go to the gym. Recommend 100% … Try it and you will see.” Posted on 11/23/2020

Review by Mick
“Best tasting mesomorph so far. Crazy energy! Fantastic muscle pump. Used to only workout with C4 for only an hour. Mesomorph will keep you going for at least 2 hours” Posted on 5/11/2019

Review by Talib
“Personally, I prefer the new formula of mesomorph over the DMAA formula. Same amount of energy, focus, and pump between the two. Why Do I prefer the Senegalia formula? Simple. I don’t get a crash of taking 1 full scoop like I did with the DMAA version.”  Posted on 10/27/2017

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Mesomorph Alternatives :

The last thing we’d want is for Mesomorph to disappear on us again. But, unfortunately in December 2021 there are still extensive delays in production with products containing DMHA. This includes fat burners like Hydroxyelite and pre workouts like Mesomorph. So if you’re here to look for a substitute until DMHA is back in Mesomorph, we got you covered.

Frankenstein Pre Workout

Up first is currently our only pre workout with DMHA available, Frankenstein. Unlike Mesomorph, Frankenstein features a fully disclosed label. So you can see it features about ~15 grams of active ingredients. When compared to Mesomorph, it shares: 

  • L-Citrulline Malate
  • Beta Alanine
  • L-Taurine
  • Caffeine
  • DMHA

And leaves 6 ingredients unique to Frankenstein:

  • Sodium
  • Betaine Anhydrous
  • L-Tyrosine
  • Acetyl L-Carnitine
  • Alpha GPC
  • Black Pepper Extract

Most of these ingredients may support endurance and focus, while Black Pepper Extract is often used in pre workouts to improve bioavailability and overall boost the impact of the other ingredients. (25,26,27,28,29,30,31)

Frankenstein Review:

“I was a huge fan of Dust X and Mesomorph but since those pre workouts aren’t available I went with this. And I am excited to say Frankenstein has filled the void perfectly! I get the same energy and pumps at the gym. Overall a great option as a replacement or to take even when the OG’s are available. I really liked the Sour Grave Worms flavor and can’t wait to try the a new flavor when this is done!”

Broken Arrow Pre Workout

Our next Mesomorph alternative is a high stimulant pre workout that features a DMAA-Like Stimulant, Citrus Aurantium Extract (Synephrine). Broken Arrow by Repp Sports similarly to Mesomorph has had several formula revisions (Read more about the original Broken Arrow Here). But in it’s current formula, Broken Arrow features ~14 grams of active ingredients. Of these ingredients, only 5 are shared with Mesomorph:

  • L-Citrulline Malate
  • Beta Alanine
  • L-Taurine
  • Caffeine
  • Theobroma Cacao Extract (Theobromine)

This leaves 6 ingredients that are different:

  • Sodium
  • Betaine Anhydrous
  • L-Tyrosine
  • Citra-Fuze Stim Blend
  • Alpha GPC
  • Black Pepper Extract

Where 5 of the remaining 6 ingredients is identical to Frankenstein. What makes Broken Arrow unique is CitraFuze Stimulant Blend. This blend of citrus-based stimulants contain synephrine, an ingredient more common in fat burners. Synephrine is a strong stimulant with thermogenic and mood boosting properties. In a pre workout, that can translate to enhanced focused and increased sweat/water weight loss. (32)

Broken Arrow Review:

“This pre workout gave me the best pumps I have ever had! You can really tell the difference the L-Citrulline Malate makes in the pre workout. The energy and pumps are unmatched. You can’t go wrong with Broken Arrow!”

Super Pump Aggression Pre Workout

Our third comparison is pretty different to Mesomorph, but hit’s all the levels of intensity we look for in the gym. Super Pump Aggression features a fully disclosed label that includes 18 grams of active ingredients. You can read more about Super Pump and Super Pump Aggression HERE.

Of these these ingredients, 5 are shared:

  • L-Citrulline
  • Beta Alanine
  • Agmatine Sulfate
  • Caffeine Anhydrous
  • Theobromine

Which leaves 8 ingredients unique to Super Pump Aggression:

  • Betaine Anhydrous
  • L-Tyrosine
  • PEA
  • Choline Bitartrate
  • DMAE
  • Black Pepper Extract
  • Rauwolfia Vomitoria Extract
  • Huperzia Serrata Extract

3 of these ingredients are shared between the other alternatives; Betaine, L-Tyrosine, and Black Pepper Extract. The remaining 5 ingredients are going to aid in supporting Super Pump Aggression’s focus complex. (33, 34,35,36,37,38)

Super Pump Aggression Review:

“I have tried many pre workouts that have extreme pumps in the advertisement, but this one by far worked the best for me. Not only are the pumps insane, but the flavors are awesome as well. My personal favorite is Fruit Punch. I would recommend this for anyone looking to improve their pumps during their workouts.”

Jack3d Pre Workout

Our last Mesomorph comparison is with another infamous OG pre workout Jack3d. Like Mesomorph, Jack3d previously featured DMAA. But Jack3d V2 now features a proprietary blend with ~4.2 grams of active ingredients per scoop and about 135mg of Caffeine per scoop. Between Mesomorph and Jack3d, 6 ingredients are shared:

  • Arginine Alpha-Ketoglutarate
  • Creatine Monohydrate
  • Beta Alanine
  • 2-Aminoisoheptane HCL
  • Geranium Extract (stem and leaves)
  • Caffeine

Which leaves 2 ingredients unique to Jack3d:

  • Yohimbe Extract
  • Schisandra Chinensis

Yohimbe is a common ingredient in fat burners due to its thermogenic properties and is similar to Rauwolfia Vomitoria. Because of their similarities, they may function in the same way. This can mean promoting energy, focus, and fat loss. (37,39) Whereas Schisandra Chinensis extract may be useful as an adaptogen and performance enhancer (4041).

Jack3d Pre Workout Review:

“Nothing has compared to the original Jack3d, but this one is very good. Solid energy, flavor, and little crash. Will definitely buy again.”

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Which Should You Try?

*Notice Of Delays*

Currently, there are a lot of delays with products in production, manufacturing, and importing. So unfortunately, your options for trying DMHA products are limited. But that’s why we write blogs, so you can find the best option available! At Same Day Supplements, we are accepting pre-orders for fat burners affected by the delays like Hellfire, Black Mamba, and Diablos. However, when it comes to pre workouts, we do currently have inventory of Mesomorph V3 and V4!

This is NOT the original formula with DMAA, we currently have a limited supply of Mesomorph V3 with Senegalia and some flavors of Mesomorph V4 with DMHA! But if you’re ready to try something new and are looking for a similar intensity to Mesomorph we would recommend trying Frankenstein or Jack3d.

For a high-stimulant complex without DMHA, both Broken Arrow and Super Pump Aggression make good alternatives. If you’re looking for a pre workout to help give you the edge in focus, Super Pump Aggression may be a better option for you. 

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This wraps up the end of our review and comparison of Mesomorph Pre Workout. Thank you for reading and if you have any questions, need a recommendation, or have a topic you want us to cover in a future blog, let us know HERE!

Looking for more to read?

Checkout some of our other blogs!

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Side Effects And Warnings:

Read entire label before taking this product. As with any supplement, check with your physician before use. Do not use this product if you have any current or previous medical condition of any kind. Such conditions may include but are not limited to the following:

  • High or low blood pressure
  • Stroke
  • Arrhythmia
  • Palpitations
  • Any heart, thyroid, or liver condition
  • Seizures
  • Anxiety or depression
  • Prostate enlargement or inflammation

Do not use if you are nursing or pregnant. Do not use if you are taking an MAOI. If any adverse symptoms occur stop use immediately and consult a physician. Keep out of reach of children.


†The intention of the information provided is for reference only and we are in no way providing medical advice or instruction. The information provided in this post is based on anecdotal information and available studies/reviews. While it is our goal to maintain and display accurate information, we can’t guarantee it represents the latest formulation of the product or information. Therefore, if you have any concerns, please visit the manufacturer’s website. Also, the information above is not a representation of our views at Same Day Supplements. Rather, these are the views and information provided by manufacturers and users. Also, the Food and Drug Administration has not evaluated these statements. Finally, the intention of these products is not to diagnose, treat, cure or prevent any disease or illness

The post Mesomorph Pre Workout : Old VS New 2022 UPDATE appeared first on Supplement Reviews Blog.


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